Hepatic Portal System
- Prof. RS Rana

- Sep 2, 2023
- 2 min read
The hepatic portal system is a specialized circulatory system within the human body that plays a crucial role in the transportation of blood from various organs and tissues to the liver. It is responsible for directing blood rich in absorbed nutrients, toxins, and other substances from the gastrointestinal tract and spleen to the liver for processing and detoxification before it enters the systemic circulation.
Here's how the hepatic portal system works:
Digestive Process: When you eat food, it gets digested in the stomach and small intestine. During digestion, nutrients from the broken-down food are absorbed into the bloodstream.
Absorption: Nutrients, along with other substances such as drugs, toxins, and waste products, are absorbed through the walls of the small intestine and transported into small blood vessels called capillaries.
Hepatic Portal Vein: Instead of directly entering the systemic circulation (which carries blood throughout the body), the nutrient-rich blood and other absorbed substances are collected into a large vein called the hepatic portal vein.
Liver Processing: The hepatic portal vein carries this blood directly to the liver. The liver is a vital organ with multiple functions, including detoxification, nutrient storage, and metabolism. In the liver, various metabolic processes occur, including the conversion of nutrients, detoxification of harmful substances, and storage of glycogen (a form of glucose).
Detoxification: One of the primary functions of the liver is to detoxify the blood by breaking down or neutralizing harmful substances like drugs and toxins. This detoxification process helps protect the body from potential harm.
Nutrient Regulation: The liver also regulates the concentration of nutrients in the bloodstream, ensuring that the body receives a consistent supply of essential substances like glucose, amino acids, and vitamins.

Release into the Systemic Circulation: After processing in the liver, the blood is filtered and modified as needed. It can then leave the liver and enter the systemic circulation, where it circulates throughout the rest of the body, delivering nutrients and other substances to various tissues.
In summary, the hepatic portal system is a unique circulatory system that directs blood from the gastrointestinal tract and spleen to the liver for processing and detoxification. It plays a crucial role in maintaining overall body function and homeostasis by ensuring that absorbed nutrients are properly metabolized and harmful substances are detoxified before they enter the systemic circulation.






Comments